This configuration of the Panasonic AV-HS6000 2 M/E Switcher includes the main frame of the switcher, featuring the input/output connectors and processing engine, and a 2 M/E control panel, both in a dual redundant power supply configuration.

The main frame offers 32 HD-SDI inputs, two DVI-D inputs for incorporating computer sources, and 16 output channels each mirrored on two SDI outputs. The main frame supports video resolutions up to 1080p at 10-bit 4:2:2 in YUV color space, and up to 1080p 8-bit 4:4:4 in RGB color space. It also accepts VESA resolutions up to 1600 x 1200 for a 4:3 aspect ratio output and 1920 x 1200 for a 16:10 output.

The control panel features two sets of bus selector buttons, crosspoint buttons, T-bars, a joystick, transition keys, display panel, and more. It also additionally supports the optional AV‑HS60C3G touchscreen menu panel, which allows quick menu operation as well as control of other functions via physical buttons and rotary encoders.